Pyrrolidine inhibitors of human cytosolic phospholipase A(2)

J Med Chem. 2000 Mar 23;43(6):1041-4. doi: 10.1021/jm9905155.
No abstract available

MeSH terms

  • Cell Line
  • Cytosol / enzymology
  • Dinoprostone / biosynthesis
  • Eicosanoids / biosynthesis
  • Enzyme Inhibitors / chemical synthesis*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Leukotriene C4 / biosynthesis
  • Phospholipases A / antagonists & inhibitors*
  • Pyrrolidines / chemical synthesis*
  • Pyrrolidines / chemistry
  • Pyrrolidines / pharmacology
  • Structure-Activity Relationship

Substances

  • Eicosanoids
  • Enzyme Inhibitors
  • Pyrrolidines
  • Leukotriene C4
  • Phospholipases A
  • Dinoprostone