The human dendritic cell marker CD83 maps to chromosome 6p23

Ann Hum Genet. 1999 Mar;63(Pt 2):181-3. doi: 10.1046/j.1469-1809.1999.6320181.x.

Abstract

The chromosomal localization of the human CD83 gene was determined using somatic cell hybrids, a radiation hybrid mapping panel and FISH analysis on human metaphase chromosomes. PCR-based analysis of a single chromosome hybrid panel identified the presence of the CD83 gene on human chromosome 6 and subsequent analysis of the Genebridge4 radiation panel located the gene between AFMa192wg9 and AFMb322wd1 with a lod score of 9.2. Finally, using FISH analysis the CD83 gene was localized to chromosome 6 band p23.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, CD
  • Biomarkers
  • CD83 Antigen
  • Chromosome Banding
  • Chromosome Mapping
  • Chromosomes, Human, Pair 6 / genetics*
  • DNA / chemistry
  • DNA / genetics
  • Dendritic Cells / metabolism*
  • Humans
  • Immunoglobulins / genetics*
  • In Situ Hybridization, Fluorescence
  • Membrane Glycoproteins / genetics*
  • Molecular Sequence Data
  • Sequence Analysis, DNA

Substances

  • Antigens, CD
  • Biomarkers
  • Immunoglobulins
  • Membrane Glycoproteins
  • DNA

Associated data

  • GENBANK/AL022396