Abstract
We report the case history of a patient with a family history of breast and ovarian cancer who was subsequently found to be a carrier of the BRCA1 gene, in whom a tiny focus of clear cell carcinoma was found at the fimbrial end of one fallopian tube when she underwent prophylactic hysterectomy and bilateral salpingoophorectomy. The implications of this finding are discussed.
MeSH terms
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Adenocarcinoma, Clear Cell / genetics*
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Breast Neoplasms / genetics
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Breast Neoplasms / prevention & control
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Breast Neoplasms / surgery
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Fallopian Tube Neoplasms / genetics*
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Female
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Genes, BRCA1 / genetics*
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Genetic Predisposition to Disease*
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Humans
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Hysterectomy
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Middle Aged
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Ovarian Neoplasms / genetics
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Ovarian Neoplasms / prevention & control
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Ovarian Neoplasms / surgery
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Ovariectomy