The role of dendritic cells in the innate immune system

Microbes Infect. 2000 Mar;2(3):257-72. doi: 10.1016/s1286-4579(00)00302-6.

Abstract

Dendritic cells (DCs) are bone-marrow-derived leucocytes that are specialised antigen-presenting cells capable of stimulating a primary T-lymphocyte response to specific antigen. In this chapter we discuss the role DCs play in the innate response acting as a critical link with the adaptive response and the influence of the innate response on dendritic cells.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antigen Presentation
  • Antigens / immunology
  • Cell Lineage / immunology
  • Cell Movement
  • Dendritic Cells / physiology*
  • Drosophila Proteins*
  • Humans
  • Immunity / physiology*
  • Membrane Glycoproteins / immunology
  • Protein Sorting Signals / immunology
  • Receptors, Antigen / immunology
  • Receptors, Cell Surface / immunology
  • Toll-Like Receptors

Substances

  • Antigens
  • Drosophila Proteins
  • Membrane Glycoproteins
  • Protein Sorting Signals
  • Receptors, Antigen
  • Receptors, Cell Surface
  • Toll-Like Receptors