Brain perfusion and neuropsychological changes in schizophrenic patients after cognitive rehabilitation

Psychiatry Res. 2000 Apr 10;98(2):127-32. doi: 10.1016/s0925-4927(99)00050-5.

Abstract

The role of cognitive variables was compared in two single cases of schizophrenia hypofrontality. SPECT procedures and neuropsychological tests were used to study frontal brain function. After cognitive rehabilitation, neuropsychological performance were enhanced in both patients, but only one of them showed enhanced the frontal blood flow. The brain perfusion changes after cognitive rehabilitation could be associated with the cognitive-dependent hypofrontality.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cognition Disorders* / diagnosis
  • Cognition Disorders* / etiology
  • Cognition Disorders* / rehabilitation
  • Frontal Lobe / blood supply*
  • Frontal Lobe / physiopathology
  • Humans
  • Male
  • Neuropsychological Tests
  • Schizophrenia / complications*
  • Schizophrenia / physiopathology
  • Tomography, Emission-Computed, Single-Photon
  • Treatment Outcome