The therapeutic management of penile tumours is determined by the degree of local extension of the tumour, and the presence of lymph node involvement and visceral metastases. Many published studies have tried to define the best treatment options as a function of tumour grade and stage. However, in daily practice, the treatment of penile tumours still remains highly controversial. After reviewing the literature, the authors discuss the various treatment options available to urologists as a function of tumour stage and recall the management difficulties related to lymph node staging.