Abstract
Enantiomerically pure cyanohydrins are important synthetic intermediates for pharmaceuticals and agrochemicals. They are produced by enzyme-catalysed synthesis using oxynitrilases. Sufficient quantities of enzyme are available via cheap natural sources and there have been recent advances in overexpression production of cyanohydrins on an industrial scale.
MeSH terms
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Aldehyde-Lyases / chemistry*
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Aldehyde-Lyases / genetics
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Aldehyde-Lyases / metabolism*
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Biochemistry / methods*
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Cloning, Molecular
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Nitriles / chemical synthesis*
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Nitriles / metabolism
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Plants / enzymology
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Recombinant Proteins / chemistry
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Recombinant Proteins / genetics
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Recombinant Proteins / metabolism
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Substrate Specificity
Substances
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Nitriles
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Recombinant Proteins
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Aldehyde-Lyases
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mandelonitrile lyase