New chemical and biological aspects of S-nitrosothiols

Curr Med Chem. 2000 Aug;7(8):821-34. doi: 10.2174/0929867003374633.

Abstract

Nitric oxide (NO) possesses many physiological effects and S-nitrosothiols have been identified in a variety of tissues exhibiting many NO-like activities. This review focuses on the latest discoveries pertaining to the biological functions of S-nitrosothiols and the recent research progress in the chemical properties and biomedical applications of RSNOs.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Chemistry, Pharmaceutical
  • Electrochemistry
  • Humans
  • Mercaptoethanol*
  • Molecular Structure
  • Nitric Oxide / metabolism*
  • Nitroso Compounds / chemistry
  • Nitroso Compounds / metabolism*
  • Penicillamine / analogs & derivatives*
  • Penicillamine / chemical synthesis
  • Protein Processing, Post-Translational / physiology
  • S-Nitroso-N-Acetylpenicillamine
  • S-Nitrosothiols*
  • Second Messenger Systems

Substances

  • Nitroso Compounds
  • S-Nitrosothiols
  • Nitric Oxide
  • Mercaptoethanol
  • S-nitrosomercaptoethanol
  • S-Nitroso-N-Acetylpenicillamine
  • Penicillamine