Combined fluphenazine and lidocaine for pain relief in head and neck cancers

Trop Doct. 2000 Apr;30(2):69-70. doi: 10.1177/004947550003000203.

Abstract

A successful method of treating intractable neoplastic pain in 12 cases is discussed. A completely new method was tried combining long-acting phenothiazine and lidocaine to achieve long-lasting pain relief. This combination gave pain relief which lasted for weeks. A possible explanation of the mechanism is offered.

MeSH terms

  • Anesthetics, Local / therapeutic use*
  • Dopamine Antagonists / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Fluphenazine / therapeutic use*
  • Head and Neck Neoplasms / complications*
  • Humans
  • Injections, Intralesional
  • Lidocaine / therapeutic use*
  • Male
  • Nerve Block / methods
  • Pain Measurement
  • Pain, Intractable / etiology*
  • Pain, Intractable / prevention & control*
  • Treatment Outcome

Substances

  • Anesthetics, Local
  • Dopamine Antagonists
  • Lidocaine
  • Fluphenazine