Abstract
The mechanisms of radiation pneumonitis have not been established. In a study on multi-field radiation therapy for lung cancer, one patient developed severe radiation pneumonitis even though the target volume was small. Radiation therapy was performed at a dose of 75 Gy in 50 fractions over five weeks. High-density areas conforming to the radiation field were observed by high-resolution CT. They were observed in the irradiated volume at doses under 20 Gy in the contralateral lung as well as in the ipsilateral lung.
MeSH terms
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Aged
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Aged, 80 and over
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Anti-Inflammatory Agents / therapeutic use
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Carcinoma, Squamous Cell / radiotherapy
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Dose Fractionation, Radiation
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Dose-Response Relationship, Radiation
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Fatal Outcome
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Humans
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Lung Neoplasms / radiotherapy*
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Male
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Methylprednisolone / therapeutic use
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Radiation Pneumonitis / diagnostic imaging
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Radiation Pneumonitis / drug therapy
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Radiation Pneumonitis / etiology*
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Radiotherapy Dosage
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Radiotherapy, Conformal / adverse effects
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Tomography, X-Ray Computed
Substances
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Anti-Inflammatory Agents
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Methylprednisolone