[Are statins indicated in the prevention of cerebral infarct?]

Rev Neurol. 2000 Apr;30(7):671-93.
[Article in Spanish]

Abstract

Introduction: Some studies of ischemic cardiopathy have shown that when pravastatin is used for the prevention of strokes, these are reduced. Whilst we await suitable clinical trials, we discuss the possible role played by these drugs in this subgroup of patients.

Development: A panel of experts from different specialties assess the data published on dislipemias in the epidemiology of strokes, the possible effect of statins in the prevention of cerebral infarcts in patients with atheromatous stenosis of the carotid artery and their mode of action.

Conclusions: Pravastatin is indicated in all patients with ictus of atheromatous origin as primary prevention of ischemic cardiopathy, in patients with strokes and hypercholesterolemia, and in patients with symptomatic or asymptomatic carotid stenosis while we wait for more specific clinical trials.

Publication types

  • English Abstract

MeSH terms

  • Anticholesteremic Agents / therapeutic use*
  • Carotid Stenosis / complications
  • Cerebral Infarction / etiology
  • Cerebral Infarction / prevention & control*
  • Humans
  • Hypercholesterolemia / complications
  • Pravastatin / therapeutic use*
  • Risk Factors

Substances

  • Anticholesteremic Agents
  • Pravastatin