Indicanine A, a new 3-phenylcoumarin from root bark of Erythrina indica

J Nat Prod. 2000 Jun;63(6):855-6. doi: 10.1021/np990300y.

Abstract

A new 3-phenylcoumarin, indicanine A (1), has been isolated from the root bark of the African medicinal plant Erythrina indica, together with three known compounds, robustic acid (2), daidzein, and 8-prenyldaidzein. The structure of the new compound was characterized, as 4-hydroxy-5-methoxy-3-(4'-methoxyphenyl)-2" -(1-methylethenyl)dihydrofurano[4",5":6,7]coumarin by means of extensive spectroscopic analyses. The compounds were found to be devoid of in vitro antibacterial activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Coumarins / chemistry
  • Coumarins / isolation & purification*
  • Coumarins / pharmacology
  • Erythrina / chemistry*
  • Escherichia coli / drug effects
  • Isoflavones / chemistry
  • Isoflavones / isolation & purification
  • Isoflavones / pharmacology
  • Microbial Sensitivity Tests
  • Mycobacterium / drug effects
  • Plant Roots / chemistry
  • Plants, Medicinal*
  • Staphylococcus aureus / drug effects

Substances

  • Coumarins
  • Isoflavones
  • indicanine A
  • robustic acid
  • daidzein