Multiple pathways allow protein secretion across the bacterial outer membrane

Curr Opin Cell Biol. 2000 Aug;12(4):420-30. doi: 10.1016/s0955-0674(00)00111-3.

Abstract

Secretion of proteins across the bacterial outer membrane takes place via a variety of mechanisms from simple one-component systems to complex multicomponent pathways. Secretion pathways can be organized into evolutionarily and functionally related groups, which highlight their relationship with organelle biogenesis. Recent work is beginning to reveal the structure and function of various secretion components and the molecular mechanisms of secretion.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Bacteria / metabolism*
  • Bacterial Proteins / metabolism*
  • Cell Membrane / metabolism
  • Humans
  • Molecular Chaperones / metabolism

Substances

  • Bacterial Proteins
  • Molecular Chaperones