This study sought to correctly preset the parameters of Mark v injection. The emphasis was laid on the flow rate in that, it ought to be set more carefully and more accurately for ensuring success in angiography. The authors analyzed the influential factors of flow rate and the relationship between flow rate and pressure limiting and hence proposed a set of typical presetting injection parameters. Experimental results demonstrated that with the contrast media concentration around 75%, high quality images could be obtained by setting the pressure limiting within 2068-5515 kPa.