Pd(PhCN)(2)Cl(2)/P(t-Bu)(3): a versatile catalyst for Sonogashira reactions of aryl bromides at room temperature

T Hundertmark; A F Littke; S L Buchwald; G C Fu

doi:10.1021/ol0058947

Pd(PhCN)(2)Cl(2)/P(t-Bu)(3): a versatile catalyst for Sonogashira reactions of aryl bromides at room temperature

Org Lett. 2000 Jun 15;2(12):1729-31. doi: 10.1021/ol0058947.

Authors

T Hundertmark¹, A F Littke, S L Buchwald, G C Fu

Affiliation

¹ Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139, USA.

PMID: 10880212
DOI: 10.1021/ol0058947

Abstract

[reaction: see text] Pd(PhCN)(2)Cl(2)/P(t-Bu)(3) serves as an efficient and a versatile catalyst for room-temperature Sonogashira reactions of aryl bromides.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Alkynes / chemical synthesis
Bromobenzenes / chemistry
Catalysis
Organometallic Compounds / chemistry*
Palladium / chemistry*
Temperature

Substances

Alkynes
Bromobenzenes
Organometallic Compounds
Palladium

Grants and funding

GM34917/GM/NIGMS NIH HHS/United States