Abstract
We describe a rare case of dedifferentiated liposarcoma with features resembling chondroblastic osteosarcoma in the dedifferentiated component. The tumor was removed from the left thigh in a 78-year-old male. It consisted of a well-differentiated liposarcoma and an anaplastic component that contained numerous osteoid and cartilaginous tissues surrounded by high-grade spindle cell sarcoma. To our knowledge, only two cases similar to the divergent chondroblastic osteosarcomatous dedifferentiation of this disease have been reported in the literature.
MeSH terms
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Aged
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Biomarkers, Tumor / analysis
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Bone Neoplasms / pathology*
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Bone Neoplasms / radiotherapy
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Bone Neoplasms / surgery
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Cell Differentiation
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Femur / diagnostic imaging
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Femur / pathology
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Femur / surgery
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Humans
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Immunohistochemistry
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Liposarcoma / radiotherapy
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Liposarcoma / secondary*
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Liposarcoma / surgery
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Lung Neoplasms / secondary
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Lung Neoplasms / surgery
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Male
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Neoplasm Proteins / analysis
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Osteosarcoma / radiotherapy
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Osteosarcoma / secondary*
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Osteosarcoma / surgery
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Radiotherapy Dosage
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Tomography, X-Ray Computed
Substances
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Biomarkers, Tumor
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Neoplasm Proteins