Integration of high resolution EEG and functional magnetic resonance in the study of human movement-related potentials

Methods Inf Med. 2000 Jun;39(2):179-82.

Abstract

Cortical sources of human movement-related potentials (i.e. unilateral finger extension) were modeled using functional magnetic resonance imaging (fMR) data as a constraint of a linear inverse source estimation from highly sampled (128 channels) EEG data. Remarkably, this estimation was performed within realistic subject's MR-constructed head models by boundary element techniques. An appropriate figure of merit served to set the optimal amount of fMR constraints. With respect to standard linear inverse source estimates, fMR-constrained ones presented increased spatial detail and provided a more reliable timing of activation in bilateral sensorimotor cortical regions of interest.

MeSH terms

  • Adult
  • Brain Mapping*
  • Cerebral Cortex / physiology*
  • Computer Simulation
  • Electroencephalography*
  • Evoked Potentials, Motor / physiology
  • Functional Laterality / physiology
  • Humans
  • Image Processing, Computer-Assisted*
  • Isometric Contraction / physiology
  • Linear Models
  • Magnetic Resonance Imaging*
  • Motor Activity / physiology*
  • Signal Processing, Computer-Assisted*