Genomic structure and chromosome location of the mouse RelA p65 gene (Rela)

E R Lemmer; J L Welch; T Tsai; C L Keck-Waggoner; C Huh; D B Zimonjic; N C Popescu; S S Thorgeirsson

doi:10.1159/000015591

Genomic structure and chromosome location of the mouse RelA p65 gene (Rela)

Cytogenet Cell Genet. 2000;89(1-2):129-32. doi: 10.1159/000015591.

Authors

E R Lemmer¹, J L Welch, T Tsai, C L Keck-Waggoner, C Huh, D B Zimonjic, N C Popescu, S S Thorgeirsson

Affiliation

¹ Laboratory of Experimental Carcinogenesis, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

PMID: 10894954
DOI: 10.1159/000015591

Abstract

The RelA (p65) subunit of transcription factor NF-kappaB plays a critical role in development, and rela(-/-) knockout mice die in utero from massive liver apoptosis. Only partial sequences of the mouse Rela gene are available. We have determined the genomic structure of mouse Rela and promoter, and have mapped the gene to chromosome 19B1-3.

MeSH terms

Animals
Base Sequence
Chromosome Banding
Chromosomes, Human, Pair 11 / genetics
Cloning, Molecular
Exons / genetics*
Humans
In Situ Hybridization, Fluorescence
Introns / genetics*
Mice
Molecular Sequence Data
NF-kappa B / genetics*
Physical Chromosome Mapping*
Promoter Regions, Genetic / genetics
Transcription Factor RelA

Substances

NF-kappa B
Transcription Factor RelA

Associated data

GENBANK/AF199371