Abstract
A case of CNS gliomyosarcoma, in a 71-year-old female with skeletal muscle differentiation is presented. The tumor was composed by two cell types: one showed features typical of glial cells, the other was constituted by elements having immunohistochemical positivity with desmin, sarcomeric actin, myoglobin and myogenin antisera. It is postulated an origin from a cell capable of dual differentiation.
Publication types
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Case Reports
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English Abstract
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Review
MeSH terms
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Actins / analysis
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Aged
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Biomarkers, Tumor / analysis
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Brain Neoplasms / chemistry
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Brain Neoplasms / diagnosis
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Brain Neoplasms / pathology*
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Cell Differentiation
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Desmin / analysis
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Diagnosis, Differential
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Fatal Outcome
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Female
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Gliosarcoma / chemistry
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Gliosarcoma / diagnosis
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Gliosarcoma / pathology*
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Humans
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Muscle Proteins / analysis
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Myogenin / analysis
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Myoglobin / analysis
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Myosarcoma / chemistry
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Myosarcoma / diagnosis
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Myosarcoma / pathology*
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Neoplasm Proteins / analysis
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Nerve Tissue Proteins / analysis
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Parietal Lobe / pathology*
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Temporal Lobe / pathology*
Substances
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Actins
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Biomarkers, Tumor
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Desmin
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MYOG protein, human
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Muscle Proteins
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Myogenin
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Myoglobin
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Neoplasm Proteins
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Nerve Tissue Proteins