Circadian changes of heart rate in West syndrome

Chronobiol Int. 2000 Jul;17(4):591-5. doi: 10.1081/cbi-100101066.

Abstract

Patterns of circadian and ultradian rhythms in the heart rate (HR) are described in a full-term baby with birth asphyxia and convulsions. A 24h HR recording was carried out at the age of 1, 15, 56, 289, and 295 days; West syndrome diagnosis was made when the patient was 3 months old. The HR showed no circadian rhythm in the follow-up, whereas it is known that the circadian rhythm appears in healthy infants at the age of 1 month and remains thereafter. This observation may be an indirect indicator of the interference of West syndrome with centers of neurological maturity.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activity Cycles / physiology
  • Age Factors
  • Circadian Rhythm / physiology*
  • Heart Rate / physiology*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Spasms, Infantile / physiopathology*