Synthesis and biological activity of 4'-methoxy derivatives of abscisic acid

Bioorg Med Chem Lett. 2000 Jul 17;10(14):1571-4. doi: 10.1016/s0960-894x(00)00302-4.

Abstract

Replacing the 4'-carbonyl group of abscisic acid with a methoxy group does not affect the abscisic acid (ABA)-like activities of the product in barley aleurone protoplasts, although the reduction of ABA to 4'-hydroxyl derivatives significantly reduces the ABA-like activity of the products. This suggests that methoxy derivatives of abscisic acid might be used to produce probes for ABA binding proteins.

MeSH terms

  • Abscisic Acid / analogs & derivatives*
  • Abscisic Acid / chemical synthesis*
  • Abscisic Acid / chemistry
  • Abscisic Acid / pharmacology
  • Drug Design
  • Enzyme Induction / drug effects
  • Hordeum / enzymology
  • Molecular Structure
  • Plant Growth Regulators / chemical synthesis*
  • Plant Growth Regulators / chemistry
  • Plant Growth Regulators / pharmacology
  • Protoplasts / drug effects
  • Protoplasts / enzymology
  • Structure-Activity Relationship
  • alpha-Amylases / biosynthesis*

Substances

  • Plant Growth Regulators
  • Abscisic Acid
  • alpha-Amylases