Lipids on the move: phosphoinositide 3-kinases in leukocyte function

Immunol Today. 2000 Jun;21(6):260-4. doi: 10.1016/s0167-5699(00)01649-2.
No abstract available

Publication types

  • Review

MeSH terms

  • Androstadienes / pharmacology
  • Animals
  • Chemotactic Factors / pharmacology
  • Chemotaxis, Leukocyte / physiology*
  • Enzyme Inhibitors / pharmacology
  • Escherichia coli Infections / enzymology
  • Escherichia coli Infections / immunology
  • Heterotrimeric GTP-Binding Proteins / physiology
  • Humans
  • Isoenzymes / antagonists & inhibitors
  • Isoenzymes / deficiency
  • Isoenzymes / genetics
  • Isoenzymes / immunology
  • Isoenzymes / physiology*
  • Leukocyte-Adhesion Deficiency Syndrome / genetics
  • Leukocytes / enzymology*
  • Macrophages, Peritoneal / enzymology
  • Macrophages, Peritoneal / physiology
  • Membrane Lipids / metabolism*
  • Mice
  • Mice, Knockout
  • Models, Biological
  • N-Formylmethionine Leucyl-Phenylalanine / pharmacology
  • Neutrophils / enzymology
  • Neutrophils / physiology
  • Peritonitis / enzymology
  • Peritonitis / immunology
  • Phosphatidylinositol 3-Kinases / deficiency
  • Phosphatidylinositol 3-Kinases / genetics
  • Phosphatidylinositol 3-Kinases / immunology
  • Phosphatidylinositol 3-Kinases / physiology*
  • Phosphatidylinositol Phosphates / metabolism
  • Phosphatidylinositols / metabolism*
  • Phosphoinositide-3 Kinase Inhibitors
  • RAC2 GTP-Binding Protein
  • Respiratory Burst
  • Signal Transduction
  • Wortmannin
  • rac GTP-Binding Proteins / deficiency
  • rac GTP-Binding Proteins / genetics

Substances

  • Androstadienes
  • Chemotactic Factors
  • Enzyme Inhibitors
  • Isoenzymes
  • Membrane Lipids
  • Phosphatidylinositol Phosphates
  • Phosphatidylinositols
  • Phosphoinositide-3 Kinase Inhibitors
  • phosphatidylinositol 3,4,5-triphosphate
  • N-Formylmethionine Leucyl-Phenylalanine
  • Heterotrimeric GTP-Binding Proteins
  • rac GTP-Binding Proteins
  • Wortmannin