The occurrence of the human glycoconjugate C(2)-alpha-D-mannosylpyranosyl-L-tryptophan in marine ascidians

A Garcia; L A Lenis; C Jiménez; C Debitus; E Quiñoá; R Riguera

doi:10.1021/ol0061384

The occurrence of the human glycoconjugate C(2)-alpha-D-mannosylpyranosyl-L-tryptophan in marine ascidians

Org Lett. 2000 Sep 7;2(18):2765-7. doi: 10.1021/ol0061384.

Authors

A Garcia¹, L A Lenis, C Jiménez, C Debitus, E Quiñoá, R Riguera

Affiliation

¹ Departamento de Química Orgánica, Facultad de Química e Instituto de Acuicultura, Universidad de Santiago de Compostela, E-15706 Santiago de Compostela, Spain.

PMID: 10964360
DOI: 10.1021/ol0061384

Abstract

[structure: see text] The C-glycoconjugate C(2)-alpha-D-mannosylpyranosyl-L-tryptophan (1), a metabolite known to be generated in humans through a novel posttranslational process, has been isolated from marine ascidians Leptoclinides dubius and Pharyngodictyon cauliflos and its N(alpha)-methyl derivative (2) from Ritterella rete.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chromatography, High Pressure Liquid
Humans
Nuclear Magnetic Resonance, Biomolecular
Tryptophan / analogs & derivatives*
Tryptophan / chemistry
Tryptophan / isolation & purification*
Urochordata / chemistry*
Urochordata / metabolism

Substances

C(2)-mannosyltryptophan
Tryptophan