Clinical and neurohormonal correlates of circulating granulocyte-macrophage colony-stimulating factor in severe heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

J T Parissis; S Adamopoulos; K F Venetsanou; D G Mentzikof; S M Karas; D T Kremastinos

doi:10.1016/s0002-9149(00)01062-6

Clinical and neurohormonal correlates of circulating granulocyte-macrophage colony-stimulating factor in severe heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

Am J Cardiol. 2000 Sep 15;86(6):707-10, A9-10. doi: 10.1016/s0002-9149(00)01062-6.

Authors

J T Parissis¹, S Adamopoulos, K F Venetsanou, D G Mentzikof, S M Karas, D T Kremastinos

Affiliation

¹ First Department of Cardiology, Amalia Fleming Hospital, Athens, Greece.

PMID: 10980234
DOI: 10.1016/s0002-9149(00)01062-6

Abstract

In this report, we showed for the first time that granulocyte-macrophage colony-stimulating factor plasma levels are elevated in patients with severe heart failure, and these levels are correlated well with neurohormonal activation and hemodynamic deterioration characterizing this syndrome.

Publication types

Comparative Study

MeSH terms

Biomarkers / blood
Cardiac Catheterization
Cardiac Output
Cardiomyopathy, Dilated / blood
Cardiomyopathy, Dilated / complications*
Cardiomyopathy, Dilated / physiopathology
Female
Granulocyte-Macrophage Colony-Stimulating Factor / blood*
Heart Failure / blood*
Heart Failure / etiology
Heart Failure / physiopathology
Humans
Male
Middle Aged
Myocardial Ischemia / blood
Myocardial Ischemia / complications*
Myocardial Ischemia / physiopathology
Prognosis
Severity of Illness Index

Substances

Biomarkers
Granulocyte-Macrophage Colony-Stimulating Factor