Omitting axillary surgery for low-risk breast cancer patients--a Swedish prospective cohort study

Acta Oncol. 2000;39(3):291-4. doi: 10.1080/028418600750013032.

Abstract

The effects of mammography screening are a decrease in the sizes of tumours and a shift in stage. Very few small breast cancers (< or = 10 mm) have lymph node metastases when screening-detected, the rate being as low as 7%. Axillary clearance is not necessary for all such small tumours. A Swedish prospective cohort study, scheduled for 1500 patients, is being launched, where axillary surgery is omitted for screening-detected breast cancers of < or = 10 mm showing Elston grade I or II/and/or S-phase < or = 10%. Axillary surgery, with the associated disadvantages, will not be performed in 970 women out of 1000 expecting an axillary recurrence rate of 3%. Nordic breast cancer centres are welcome to join the study, which has already recruited around 500 patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Axilla / surgery
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Female
  • Humans
  • Lymph Node Excision*
  • Lymph Nodes / pathology*
  • Middle Aged
  • Patient Selection
  • Prognosis
  • Prospective Studies
  • Research Design
  • Risk Factors