Microalbuminuria is associated with abnormal thoracic aortic mechanics in essential hypertension

Am J Cardiol. 2000 Oct 1;86(7):797-801, A9. doi: 10.1016/s0002-9149(00)01087-0.

Abstract

In a population of 162 patients with currently untreated essential hypertension, those with microalbuminuria (n = 75) had significantly impaired elastic properties of the proximal ascending thoracic aorta compared with their normoalbuminuric counterparts (n = 87), whereas urinary albumin excretion was a significant predictor of aortic mechanics in the entire population. Impaired aortic mechanics in microalbuminuric hypertensives were not fully accounted for by clustering of classic risk factors for atherosclerosis, and constitute a finding that may entail additional long-term cardiovascular risk in this subgroup of patients.

MeSH terms

  • Adult
  • Aged
  • Albuminuria / physiopathology*
  • Aorta, Thoracic / physiopathology*
  • Echocardiography
  • Humans
  • Hypertension / physiopathology*
  • Hypertension / urine*
  • Middle Aged