Abstract
Ten unrelated Hafnia alvei clinical isolates were grouped according to either their low-level and inducible cephalosporinase production or their high-level and constitutive cephalosporinase production phenotype. Their AmpC sequences shared 85 to 100% amino acid identity. The immediate genetic environment of ampC genes was conserved in H. alvei isolates but was different from that found in other ampC-possessing enterobacterial species.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Ceftazidime / pharmacology*
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Cephalosporinase / genetics*
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Cephalosporinase / metabolism
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Drug Resistance, Microbial
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Electrophoresis, Gel, Pulsed-Field
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Fenoterol
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Genes, Bacterial*
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Genetic Variation
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Hafnia alvei / drug effects
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Hafnia alvei / enzymology
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Hafnia alvei / genetics*
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Hafnia alvei / metabolism
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Humans
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Plasmids / genetics
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Sequence Homology, Amino Acid
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beta-Lactamases / metabolism
Substances
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Fenoterol
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Ceftazidime
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Cephalosporinase
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beta-Lactamases
Associated data
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GENBANK/AF180953
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GENBANK/AF180954
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GENBANK/AF180955
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GENBANK/AF180956
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GENBANK/AF180957
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GENBANK/AF180958
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GENBANK/AF180959
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GENBANK/AF180960
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GENBANK/AF180961