Clinical evaluation of a novel chromogenic agar dipslide for diagnosis of urinary tract infections

Eur J Clin Microbiol Infect Dis. 2000 Sep;19(9):694-8. doi: 10.1007/s100960000345.

Abstract

The performance of a novel dipslide (DipStreak; Novamed, Israel) consisting of chromogenic agar (Uriselect 3; Sanofi Pasteur, France) and blood agar media was evaluated prospectively and compared to that of conventional urine culture for the diagnosis of urinary tract infection. A total of 1070 clean-catch urine specimens obtained from 251 hospitalized patients and 819 outpatients were processed. The overall performance of the DipStreak was as follows: sensitivity, 95.7%; specificity, 99.2%; agreement, 89.8%; accuracy, 98%; positive predictive value, 98.5%; and negative predictive value, 97.7%. A total of 270 urine specimens were positive by both DipStreak and conventional culture. The chromogenic agar allowed rapid identification of organisms in 211 (78.1%) cultures, while isolates in the other 59 (21.9%) cultures remained unidentified. The results indicate that the DipStreak device coupled with the Uriselect 3 agar represents a convenient and accurate method for inoculation of urine specimens, quantitation of bacteria, diagnosis of significant bacteriuria, and presumptive identification of isolates.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Bacteria / classification*
  • Bacteria / growth & development
  • Bacteria / isolation & purification
  • Bacterial Infections / diagnosis
  • Bacterial Infections / microbiology
  • Candida / classification*
  • Candida / growth & development
  • Candida / isolation & purification
  • Candidiasis / diagnosis
  • Candidiasis / microbiology
  • Chromogenic Compounds / metabolism*
  • Culture Media
  • Humans
  • Predictive Value of Tests
  • Reagent Kits, Diagnostic*
  • Sensitivity and Specificity
  • Urinary Tract Infections / diagnosis*
  • Urinary Tract Infections / microbiology

Substances

  • Chromogenic Compounds
  • Culture Media
  • Reagent Kits, Diagnostic