Abstract
A 37-year old woman presented with severe endometriosis and the patient underwent a conservative operation. We investigated the effect of treatment with danazol on the levels of CA-125, CA-19-9, CA 15-3, SIL-2R, IL-6, IL-1a, TNE-a, SCD8 and SCD4 in this woman. Our findings suggest that severe endometriosis is a condition which induces a rise of tumor markers and cytokine levels that are suppressed on danazol treatment.
MeSH terms
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Adult
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Biomarkers, Tumor / blood*
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CA-125 Antigen / blood
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CA-19-9 Antigen / blood
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CD4 Antigens / blood
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CD8 Antigens / blood
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Cytokines / blood*
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Danazol / therapeutic use*
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Endometriosis / blood
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Endometriosis / drug therapy*
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Female
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Follow-Up Studies
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Humans
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Interleukin-1 / blood
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Interleukin-6 / blood
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Mucin-1 / blood
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Receptors, Interleukin-2 / analysis
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Tumor Necrosis Factor-alpha / analysis
Substances
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Biomarkers, Tumor
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CA-125 Antigen
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CA-19-9 Antigen
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CD4 Antigens
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CD8 Antigens
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Cytokines
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Interleukin-1
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Interleukin-6
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Mucin-1
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Receptors, Interleukin-2
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Tumor Necrosis Factor-alpha
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Danazol