Frequency, risk factors, and clinical outcomes of left ventricular assist device-associated ventricular thrombus

Am J Cardiol. 2000 Nov 15;86(10):1156-9, A10. doi: 10.1016/s0002-9149(00)01182-6.

Abstract

A retrospective, transesophageal study of 51 consecutive patients receiving a left ventricular (LV) assist device (AD) over a 2-year period showed that LVAD-associated LV thrombosis (16%) was predicted by acute myocardial infarction, atrial cannulation, and postimplantation bleeding, and was associated with a fourfold increased risk of stroke compared with patients without thrombosis. LV cannulation, when using short-term LVADs, may decrease the incidence of LV thrombosis, and early transition to Heartmate-LVAD support may improve outcome.

MeSH terms

  • Aged
  • Analysis of Variance
  • Coronary Disease / complications
  • Coronary Disease / therapy
  • Echocardiography, Transesophageal
  • Equipment Failure
  • Female
  • Heart Diseases / diagnostic imaging
  • Heart Diseases / etiology*
  • Heart Diseases / mortality
  • Heart Diseases / therapy
  • Heart Ventricles*
  • Heart-Assist Devices / adverse effects*
  • Humans
  • Incidence
  • Logistic Models
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Retrospective Studies
  • Risk Factors
  • Thrombosis / diagnostic imaging
  • Thrombosis / etiology*
  • Thrombosis / mortality
  • Thrombosis / therapy
  • Treatment Outcome