[Expression of the survivin gene in normal and hyperplastic endometrium]

Ginekol Pol. 2000 Sep;71(9):1226-9.
[Article in Polish]

Abstract

Objective: Surviving a novel anti-apoptotic gene is expressed during fetal development and in numerous human cancers.

Material and methods: We analyzed the expression of surviving in human normal endometrium: proliferative n = 8, secretive n = 4 cases and hyperplastic endometrium 6 cases.

Results: RT-PCR revealed surviving expression in all cases of normal and hyperplastic endometrium. The highest expression of surviving gene was observed in hyperplastic endometrium and in the late proliferative phase.

Publication types

  • English Abstract

MeSH terms

  • Apoptosis / genetics*
  • Endometrium / cytology*
  • Endometrium / pathology
  • Female
  • Gene Expression / genetics
  • Gene Expression Regulation, Neoplastic / genetics*
  • Humans
  • Hyperplasia / pathology
  • Menstrual Cycle / genetics
  • Reverse Transcriptase Polymerase Chain Reaction