A 41-year-old man with 16 radial keratotomy (RK) incisions in each eye reported a paradoxical diurnal variation in vision in both eyes with low Dk/L soft contact lenses. After rk, the patient experienced the conventional diurnal change a morning-to-evening mean (right and left eyes) myopic change of -1.80 diopters (D). However, while wearing low Dk/L contact lenses, a paradoxical morning-to-evening mean hyperopic change of 2.30 D was found. The diurnal variation was minimized (0.50 D) by wearing high Dk/L contact lenses. These results suggest that contact lenses can be used to treat diurnal variation in manifest refraction after RK by inducing appropriate stress.