Preparation of new anti-tubulin ligands through a dual-mode, addition-elimination reaction to a bromo-substituted alpha, beta-unsaturated sulfoxide

J Org Chem. 2000 Dec 15;65(25):8811-5. doi: 10.1021/jo0004761.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bromine / chemistry*
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Safrole / analogs & derivatives*
  • Safrole / chemistry*
  • Tubulin / metabolism
  • Tubulin Modulators*

Substances

  • Ligands
  • Tubulin
  • Tubulin Modulators
  • Safrole
  • Bromine
  • sulfoxide