Intracerebroventricular corticotropin-releasing factor decreases food intake in white-crowned sparrows

Physiol Behav. 2000 Oct;71(1-2):213-6. doi: 10.1016/s0031-9384(00)00326-7.

Abstract

Neuropeptides such as corticotropin-releasing factor (CRF) may play a role in regulating the pronounced seasonal changes in food intake shown by white-crowned sparrows (Zonotrichia leucophrys gambelii). White-crowned sparrows held on short day length received injections into the third ventricle (icv) of saline or 5.0, 15.0, and 30 microg/kg. Meal size over the subsequent 180 min was significantly depressed in a dose-dependent fashion. Other non-specific behaviors such as preening, hopping, and immobile behaviors appeared to not be affected by a dose that suppressed food intake. This experiment suggests that white-crowned sparrows, when weight-stable, respond to CRF in a manner comparable with several mammalian species.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Corticotropin-Releasing Hormone / administration & dosage
  • Corticotropin-Releasing Hormone / pharmacology*
  • Depression, Chemical
  • Dose-Response Relationship, Drug
  • Eating / drug effects*
  • Injections, Intraventricular
  • Photoperiod
  • Songbirds / physiology*

Substances

  • Corticotropin-Releasing Hormone