Superiority of end-to-end versus telescoped bronchial anastomosis in single lung transplantation for pulmonary emphysema

J Thorac Cardiovasc Surg. 2001 Jan;121(1):149-154. doi: 10.1067/mtc.2001.110188.

Abstract

Objective: To assess the influence of surgical technique (telescoped versus end-to-end anastomosis) on the incidence of bronchial anastomotic complications in patients who underwent single lung transplantation for pulmonary emphysema.

Methods: Seventy-six adult recipients of single lung transplants for pulmonary emphysema were evaluated for the presence of 3 types of major bronchial anastomotic complications: ischemia, dehiscence, and severe stenosis. Surgical technique, clinical course, and mortality were reviewed retrospectively.

Results: The 3 major complications were observed in 11 (34%; ischemia), 8 (25%; dehiscence), and 11 (34%; severe stenosis) of 32 telescoped bronchial anastomoses. In contrast, ischemia, dehiscence, and severe stenosis occurred in only 4 (9%), 1 (2%), and 2 (5%) of 44 end-to-end anastomoses (P =.0087, P =.0034, and P =.0012, respectively). The relative risk of ischemia, dehiscence, and severe stenosis in telescoped anastomoses was 2.1, 2.5, and 2.5, respectively, compared with end-to-end anastomoses. Five (13%) telescoped anastomoses required stent placement as compared with only 2 (5%) end-to-end anastomoses (P =.1244). Early postoperative pneumonia was more common in the telescoped anastomosis group (56%) than in the end-to-end group (32%; P =.0380). There was a trend toward shorter survival in the telescoped anastomosis group (mean survival 1045 +/- 145 days) as compared with the end-to-end group (mean survival 1289 +/- 156 days), but these differences did not achieve statistical significance (P =.2410).

Conclusions: In patients who underwent single lung transplantation for pulmonary emphysema, telescoped anastomoses were associated with a higher incidence of bronchial anastomotic complications than end-to-end anastomoses.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Anastomosis, Surgical / adverse effects
  • Anastomosis, Surgical / methods
  • Anastomosis, Surgical / mortality
  • Bronchi / blood supply
  • Bronchi / pathology
  • Bronchi / surgery*
  • Bronchoscopy
  • Constriction, Pathologic / epidemiology
  • Constriction, Pathologic / etiology
  • Female
  • Humans
  • Incidence
  • Ischemia / epidemiology
  • Ischemia / etiology
  • Lung Transplantation* / adverse effects
  • Lung Transplantation* / methods
  • Lung Transplantation* / mortality
  • Male
  • Middle Aged
  • Prognosis
  • Pulmonary Emphysema / surgery*
  • Retrospective Studies
  • Survival Rate