qBrn-2, a POU III gene in quail: distinct developmental expression revealed by a specific antibody

Mech Dev. 2001 Feb;100(2):349-52. doi: 10.1016/s0925-4773(00)00531-1.

Abstract

We examined qBrn-2 protein expression in quail from its onset to final profile with a specific antibody we prepared. qBrn-2 expression employed onset-widespread-restriction pattern, and precisely concurred with formation and differentiation of neural tube. qBrn-2 protein was also located outside neural tube. Obvious differences in expression were observed compared with that of Brn-2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Western
  • Brain / embryology
  • Brain / metabolism
  • Cell Differentiation
  • Coturnix
  • DNA, Complementary / metabolism
  • DNA-Binding Proteins / biosynthesis*
  • DNA-Binding Proteins / genetics*
  • Embryo, Nonmammalian
  • Gene Expression Regulation, Developmental
  • Gene Library
  • Homeodomain Proteins
  • Immunohistochemistry
  • Neural Crest / embryology*
  • Neural Crest / metabolism*
  • POU Domain Factors
  • Time Factors
  • Tissue Distribution
  • Transcription Factors / biosynthesis*
  • Transcription Factors / genetics*

Substances

  • DNA, Complementary
  • DNA-Binding Proteins
  • Homeodomain Proteins
  • POU Domain Factors
  • Transcription Factors
  • transcription factor Brn-2