A new dammarane-type triterpene glycoside from Polyscias fulva

E Bedir; N J Toyang; I A Khan; L A Walker; A M Clark

doi:10.1021/np0003589

A new dammarane-type triterpene glycoside from Polyscias fulva

J Nat Prod. 2001 Jan;64(1):95-7. doi: 10.1021/np0003589.

Authors

E Bedir¹, N J Toyang, I A Khan, L A Walker, A M Clark

Affiliation

¹ National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, and Departments of Pharmacognosy and Pharmacology, School of Pharmacy, University of Mississippi, University, Mississippi 38677, USA.

PMID: 11170676
DOI: 10.1021/np0003589

Abstract

A new dammarane-type triterpene glycoside, polysciasoside A (1), and three known compounds have been isolated from the leaves of Polyscias fulva. The structure of the new compound was established as 12-oxo-3beta,16beta,20(S)-trihydroxydammar-24-ene-3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Anti-Infective Agents / chemistry
Anti-Infective Agents / isolation & purification*
Anti-Infective Agents / pharmacology
Cameroon
Candida albicans / drug effects
Chromatography, Thin Layer
Cryptococcus neoformans / drug effects
Dammaranes
Glycosides / chemistry*
Glycosides / isolation & purification*
Glycosides / pharmacology*
Magnetic Resonance Spectroscopy
Mass Spectrometry
Microbial Sensitivity Tests
Plants, Medicinal / chemistry*
Steroids / chemistry
Trees
Triterpenes / chemistry*
Triterpenes / isolation & purification*
Triterpenes / pharmacology*

Substances

Anti-Infective Agents
Glycosides
Steroids
Triterpenes
polysciasoside A