Treatment of recurrent or progressive malignant glioma with a recombinant adenovirus expressing human interferon-beta (H5.010CMVhIFN-beta): a phase I trial

Hum Gene Ther. 2001 Jan 1;12(1):97-113. doi: 10.1089/104303401451013.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I
  • Comparative Study

MeSH terms

  • Adenoviridae / genetics*
  • Adenoviridae / metabolism
  • Adolescent
  • Adult
  • Animals
  • Brain Neoplasms / metabolism
  • Brain Neoplasms / mortality
  • Brain Neoplasms / therapy*
  • Brain Neoplasms / virology
  • Gene Expression
  • Genetic Therapy*
  • Glioma / metabolism
  • Glioma / mortality
  • Glioma / therapy*
  • Glioma / virology
  • Humans
  • Interferon-beta / biosynthesis*
  • Macaca mulatta / genetics
  • Macaca mulatta / virology
  • Magnetic Resonance Imaging
  • Mice
  • Mice, Inbred C57BL
  • Recurrence
  • Risk Assessment
  • Safety
  • Survival Rate
  • Treatment Outcome

Substances

  • Interferon-beta