Prevalence of hepatitis C among injection drug users in England and Wales: is harm reduction working?

Am J Public Health. 2001 Jan;91(1):38-42. doi: 10.2105/ajph.91.1.38.

Abstract

Objectives: This study sought to establish the prevalence of hepatitis C antibodies (anti-HCV) and hepatitis B antibodies (anti-HBc) among injection drug users in England and Wales.

Methods: A voluntary cross-sectional survey collected oral fluid samples and behavioral information; 2203 injectors were recruited through drug agencies, and 758 were recruited in the community.

Results: Prevalence was 30% for anti-HCV, 21% for anti-HBc, and 0.9% for HIV antibodies. Anti-HCV prevalence rates were significantly greater among those with longer injecting careers, those in older age groups, those residing in London, those recruited in drug agencies, those positive for anti-HBc, and those with a previous voluntary HIV test.

Conclusions: Anti-HCV prevalence rates among injectors in England and Wales, where comprehensive harm reduction programs exist, are lower than rates in other industrialized countries.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • England / epidemiology
  • Female
  • Hepatitis B / epidemiology
  • Hepatitis C / epidemiology
  • Hepatitis C / prevention & control*
  • Hepatitis C / transmission
  • Humans
  • Incidence
  • Logistic Models
  • Male
  • Odds Ratio
  • Risk Factors
  • Seroepidemiologic Studies
  • Substance Abuse, Intravenous / virology*
  • Wales / epidemiology