Detection of genes for alkane and naphthalene catabolism in Rhodococcus sp. strain 1BN

Environ Microbiol. 2000 Oct;2(5):572-7. doi: 10.1046/j.1462-2920.2000.00134.x.

Abstract

Rhodococcus sp. 1BN was isolated from a contaminated site and showed various biodegradative capabilities. Besides naphthalene, strain 1BN degraded medium- (C6) and long-chain alkanes (C16-C28), benzene and toluene, alone or when the hydrocarbons were mixed in equal proportions. The nucleotide sequence of an alk polymerase chain reaction (PCR) fragment revealed a 59% nucleotide homology to the Pseudomonas oleovorans alkB gene. The nar fragments were highly homologous to genes coding for large and small subunits of cis-naphthalene 1,2-dioxygenase (narAa and narAb) and to cis-naphthalene dihydrodiol dehydrogenase (narB) from other rhodococci. The oxidation of indene to cis-(1S,2R)-1,2-dihydroxyindan by toluene-induced cells allows to hypothesize that strain 1BN also carries a toluene dioxygenase-like system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkanes / metabolism*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Chromatography, High Pressure Liquid
  • Cytochrome P-450 CYP4A
  • Cytochrome P-450 Enzyme System / genetics
  • Cytochrome P-450 Enzyme System / metabolism
  • Genes, Bacterial*
  • Indenes / metabolism
  • Mixed Function Oxygenases / genetics
  • Mixed Function Oxygenases / metabolism
  • Molecular Sequence Data
  • Naphthalenes / metabolism*
  • Nitrate Reductase
  • Nitrate Reductases / genetics
  • Nitrate Reductases / metabolism
  • Oxidation-Reduction
  • Oxygenases / metabolism
  • Protein Subunits
  • Pseudomonas / genetics*
  • Pseudomonas / metabolism
  • Rhodococcus / genetics*
  • Rhodococcus / metabolism
  • Sequence Homology, Nucleic Acid
  • Toluene / metabolism

Substances

  • Alkanes
  • Bacterial Proteins
  • Indenes
  • Naphthalenes
  • Protein Subunits
  • narA protein, Bacillus subtilis
  • naphthalene
  • Toluene
  • indene
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • Oxygenases
  • toluene dioxygenase
  • Cytochrome P-450 CYP4A
  • Nitrate Reductases
  • Nitrate Reductase

Associated data

  • GENBANK/AJ401611
  • GENBANK/AJ401612
  • GENBANK/AJ401613