[Management of premature rupture of the membranes at term: how long to delay? Results of a prospective multicentric study in 713 cases]

J Gynecol Obstet Biol Reprod (Paris). 2001 Feb;30(1):42-50.
[Article in French]

Abstract

Objective: The aim of our study was to define he best delay for management of spontaneous rupture of the membranes at term.

Materials and methods: We conducted a prospective multicentric study in western France defining 3 groups of expectancy (6, 12 and 24 hours) to assess obstetrical, neonatal and maternal outcomes.

Results: We included 713 patients. There was no significant difference in neonatal and maternal morbidity between the 3 groups. The rate of cesarean section was statistically higher in the 6-hour group (12%). There was no statistical difference between 12 and 24 hours but the rate was lower in the 12-hour group (5.5 versus 7.9%).

Conclusion: Based on our findings and a review of the literature, we have decided that in cased of premature rupture of the membranes at term, a 12 hour delay is best. At most two prostaglandin maturations can be performed in unfavorable cervixes.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial
  • English Abstract
  • Multicenter Study

MeSH terms

  • Adult
  • Cesarean Section / standards
  • Cesarean Section / statistics & numerical data
  • Clinical Protocols / standards
  • Female
  • Fetal Membranes, Premature Rupture / complications
  • Fetal Membranes, Premature Rupture / diagnosis
  • Fetal Membranes, Premature Rupture / therapy*
  • France / epidemiology
  • Humans
  • Labor, Induced / methods*
  • Labor, Induced / standards
  • Labor, Induced / statistics & numerical data
  • Morbidity
  • Patient Selection
  • Pregnancy
  • Pregnancy Outcome / epidemiology
  • Prognosis
  • Prospective Studies
  • Time Factors