The pathogenic factors of laryngeal cancer in Yanbian area of China were investigated by analyzing the clinical characteristic of laryngeal cancer patients treated in Yanbian hospital from February 1981 to February 1992. The results showed that the peak period for the occurrence of this disease was at the ages between 50 and 69. The ratio of female patients to males was much lower than that found in Northeast Area of China. The onset of laryngeal cancer had been increasing since 1982 and remained high even in 1990s. The penetrating site was most frequently found in supraglottic portion, and the squamous cell carcinoma was the most common pathologic type. Laryngeal cancer was related to cigarette smoking to which the female patients were more sensitive than males. However, no definite reference was found between drinking and laryngeal cancer.