Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice

Transplant Proc. 2001 Feb-Mar;33(1-2):863-4. doi: 10.1016/s0041-1345(00)02352-6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoviridae / genetics
  • Animals
  • Apoptosis
  • Enzyme Induction
  • Lipid Peroxidation
  • Liver / blood supply*
  • Liver / enzymology
  • Liver / pathology
  • Mice
  • Mice, Inbred C57BL
  • NF-kappa B / metabolism
  • Necrosis
  • Reactive Oxygen Species / metabolism*
  • Reperfusion Injury / enzymology
  • Reperfusion Injury / pathology
  • Reperfusion Injury / prevention & control*
  • Transfection*
  • rac1 GTP-Binding Protein / antagonists & inhibitors*
  • rac1 GTP-Binding Protein / genetics

Substances

  • NF-kappa B
  • Reactive Oxygen Species
  • rac1 GTP-Binding Protein