[Low-grade malignant peripheral nerve sheath tumor of the neck soft tissues]

Laryngorhinootologie. 2001 Jan;80(1):39-42. doi: 10.1055/s-2001-11034.
[Article in German]

Abstract

Background: Malignant Peripheral Nerve Sheath Tumours (MPNST) either grow sporadically, after radiation or chemotherapy respectively. In many cases they are associated with Neurofibromatosis I. Because of the multiform histologic picture they are often difficult to differentiate from other soft tissue tumours.

Patient: We present the case of a sporadic MPNST which developed from the vagus nerve of a 39-year-old patient following radiation of the neck 7 years before. After complete excision there has been no recurrence up to now.

Results and conclusions: Sporadic MPNST of the head and neck are comparatively rare. With regard to the strong association with Neurofibromatosis I and the difficult differential diagnosis to other soft tissue tumours the emphasis should be put on excluding further manifestations of Neurofibromatosis I and of secondary tumours.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Cell Transformation, Neoplastic / pathology
  • Cranial Nerve Neoplasms / diagnosis*
  • Cranial Nerve Neoplasms / pathology
  • Cranial Nerve Neoplasms / surgery
  • Diagnosis, Differential
  • Female
  • Head and Neck Neoplasms / diagnosis*
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / surgery
  • Humans
  • Neoplasms, Radiation-Induced / diagnosis*
  • Neoplasms, Radiation-Induced / pathology
  • Neoplasms, Radiation-Induced / surgery
  • Nerve Sheath Neoplasms / diagnosis*
  • Nerve Sheath Neoplasms / pathology
  • Nerve Sheath Neoplasms / surgery
  • Neurofibromatosis 1 / diagnosis
  • Neurofibromatosis 1 / pathology
  • Neurofibromatosis 1 / surgery
  • Soft Tissue Neoplasms / diagnosis*
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / surgery
  • Vagus Nerve / pathology
  • Vagus Nerve Diseases / diagnosis*
  • Vagus Nerve Diseases / pathology
  • Vagus Nerve Diseases / surgery