Genetic counselling for schizophrenia in the era of molecular genetics

Can J Psychiatry. 2001 Mar;46(2):123-30. doi: 10.1177/070674370104600202.

Abstract

Objective: To review the role of genetic counselling for individuals with psychiatric illnesses.

Method: Using schizophrenia as an example and including updated information about a genetic subtype (22q deletion syndrome), we discuss the value of the genetic counselling process in psychiatry, with support from the literature and our clinical experience.

Results: Genetic counselling, the process through which knowledge about the genetics of illnesses is shared, provides information on the inheritance of illnesses and their recurrence risks; addresses the concerns of patients, their families, and their health care providers; and supports patients and their families dealing with these illnesses. For comprehensive medical management, this service should be available to all individuals with schizophrenia and their families.

Conclusions: New findings in the genetics of psychiatric illness may have important clinical implications for patients and their families.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Chromosome Deletion
  • Chromosomes, Human, Pair 22
  • Genetic Counseling*
  • Humans
  • Molecular Biology*
  • Risk Factors
  • Schizophrenia / genetics*
  • Schizophrenia / prevention & control