Self-reported effectiveness and physician consultation rate in users of over-the-counter histamine-2 receptor antagonists

Am J Gastroenterol. 2001 Mar;96(3):673-6. doi: 10.1111/j.1572-0241.2001.03602.x.

Abstract

Objective: Decreased physician visits for dyspepsia were predicted with the histamine-2 receptor antagonists (H2RA) release to over-the-counter (OTC) status. The aim of this study was to examine the presentation frequency for dyspeptic complaints before and after the OTC release of the H2RA and the self-reported effectiveness of OTC H2RA.

Methods: Two cross-sectional surveys were used in a community sample. The patients comprised a random age- and sex-stratified sample of 1600 ambulatory adults in 1993 and 1800 in 1997. Self-report, valid mail surveys gathered information on healthcare seeking and gastrointestinal symptoms in 1993 and 1997 and antisecretory use in 1997.

Results: Presentation frequency for dyspepsia was 22% in 1993 versus 23.5% in 1997. Only 16% of chronic users of the OTC H2RA obtained complete relief of symptomatic episodes. Use of an OTC H2RA was highly associated with presentation to a physician in the past year.

Conclusions: OTC H2RA infrequently provided the complete relief desired by patients. Presentation frequency to physicians for dyspeptic complaints did not change with availability of H2RA OTC.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Data Collection*
  • Dyspepsia / drug therapy*
  • Dyspepsia / epidemiology
  • Female
  • Histamine H2 Antagonists / standards*
  • Histamine H2 Antagonists / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Minnesota
  • Nonprescription Drugs / standards*
  • Nonprescription Drugs / therapeutic use*
  • Office Visits / statistics & numerical data*
  • Patient Acceptance of Health Care
  • Prevalence

Substances

  • Histamine H2 Antagonists
  • Nonprescription Drugs