Two types of auditory neglect

Brain. 2001 Apr;124(Pt 4):676-87. doi: 10.1093/brain/124.4.676.

Abstract

Auditory neglect, defined as inattention to stimuli within the left hemispace, is mostly reported in association with left ear extinction in dichotic listening. However, it remains disputed as to how far dichotic extinction reflects a primary attentional deficit and is thus appropriate for the diagnosis of auditory neglect. We report here on four patients who presented left ear extinction in dichotic listening following right unilateral hemispheric lesions. Auditory spatial attention was assessed with two additional tasks: (i) diotic test by means of interaural time differences (ITDs), simulating bilateral simultaneous spatial presentation of the dichotic tasks without the inconvenience of interaural intensity or content difference; and (ii) sound localization. A hemispatial asymmetry on the ITD diotic test or a spatial bias on sound localization were found to be part of auditory neglect. Two patients (J.C.N. and M.B.) presented a marked hemispatial asymmetry favouring the ipsilesional hemispace in the ITD diotic test, but did not show any spatial bias in sound localization. Two other patients (A.J. and E.S.) had the reverse profile: no hemispatial asymmetry in the ITD diotic test, but a severe spatial bias directed to the ipsilesional side in sound localization. J.C.N. and M.B. had mainly subcortical lesions affecting the basal ganglia. A.J. and E.S. had cortical lesions in the prefrontal, superior temporal and inferior parietal areas. Thus, there are two behaviourally and anatomically distinct types of auditory neglect characterized by: (i) deficit in allocation of auditory spatial attention following lesions centred on basal ganglia; or (ii) distortion of auditory spatial representation following frontotemporoparietal lesions.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Attention
  • Basal Ganglia Cerebrovascular Disease / complications
  • Basal Ganglia Cerebrovascular Disease / pathology
  • Basal Ganglia Cerebrovascular Disease / physiopathology
  • Brain Ischemia / complications
  • Cerebral Hemorrhage / complications
  • Dichotic Listening Tests
  • Extinction, Psychological
  • Female
  • Functional Laterality
  • Humans
  • Male
  • Middle Aged
  • Parietal Lobe / pathology
  • Parietal Lobe / physiopathology
  • Perceptual Disorders / classification
  • Perceptual Disorders / diagnosis*
  • Perceptual Disorders / etiology
  • Perceptual Disorders / physiopathology*
  • Prefrontal Cortex / pathology
  • Prefrontal Cortex / physiopathology
  • Sound Localization*
  • Temporal Lobe / pathology
  • Temporal Lobe / physiopathology