Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages

MeSH terms

• Acetyltransferases / metabolism
• Biopsy
• Bronchi / enzymology
• Bronchi / pathology
• Bronchoalveolar Lavage
• Cytokines / biosynthesis*
• Cytokines / metabolism
• Dexamethasone / pharmacology*
• Gene Expression
• Glucocorticoids / pharmacology
• Histone Acetyltransferases
• Histone Deacetylase 2
• Histone Deacetylases / biosynthesis
• Histone Deacetylases / metabolism*
• Humans
• Macrophages, Alveolar / drug effects*
• Oxidative Stress / physiology
• Repressor Proteins*
• Saccharomyces cerevisiae Proteins*
• Smoking / genetics
• Smoking / metabolism*
• Smoking / pathology