Involvement of sphingomyelinase in insulin-induced phosphatidylinositol 3-kinase activation

FASEB J. 2001 Apr;15(6):1113-4. doi: 10.1096/fj.00-0520fje.

Authors

C Huang¹, W Y Ma, M Ding, J Li, X Shi, V Castranova, V Vallyathan, A M Bode, Z Dong

Affiliation

¹ The Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.

PMID: 11292685
DOI: 10.1096/fj.00-0520fje

No abstract available

MeSH terms

Animals
Cells, Cultured
Drug Interactions
Enzyme Activation / drug effects
Enzyme Induction / drug effects
Epidermis / drug effects*
Epidermis / enzymology
Hexachlorocyclohexane / analogs & derivatives
Hexachlorocyclohexane / pharmacology
Insulin / pharmacology*
Mice
Phosphatidylinositol 3-Kinases / metabolism*
Platelet Aggregation Inhibitors / pharmacology
Sphingomyelin Phosphodiesterase / metabolism
Sphingomyelin Phosphodiesterase / physiology*
Sphingosine / analogs & derivatives*
Sphingosine / pharmacology
Tumor Cells, Cultured

Substances

Insulin
N-acetylsphingosine
Platelet Aggregation Inhibitors
Hexachlorocyclohexane
1,3,4,5,6-pentachlorocyclohexene-1-oxide
Phosphatidylinositol 3-Kinases
Sphingomyelin Phosphodiesterase
Sphingosine