Isolated digital vasculitis in a patient with rheumatoid arthritis: good response to tumour necrosis factor alpha blocking treatment

A A den Broeder; F H van den Hoogen; L B van de Putte

doi:10.1136/ard.60.5.538

Isolated digital vasculitis in a patient with rheumatoid arthritis: good response to tumour necrosis factor alpha blocking treatment

Ann Rheum Dis. 2001 May;60(5):538-9. doi: 10.1136/ard.60.5.538.

Authors

A A den Broeder¹, F H van den Hoogen, L B van de Putte

Affiliation

¹ Department of Rheumatology, University Medical Centre Nijmegen, The Netherlands. [email protected]

Abstract

Tumour necrosis factor alpha (TNFalpha) blocking agents are among the most promising new treatments for rheumatoid arthritis (RA). However, no data exist about the effect of these agents on extra-articular manifestations of RA. A patient is described with small vessel vasculitis that repeatedly responded well to treatment with the soluble p55 TNFalpha receptor fusion protein Ro 45-2081 (lenercept).

Publication types

Case Reports

MeSH terms

Arthritis, Rheumatoid / complications*
Arthritis, Rheumatoid / drug therapy
Female
Fingers / blood supply*
Humans
Immunoglobulin Heavy Chains / therapeutic use*
Immunoglobulin gamma-Chains
Middle Aged
Receptors, Tumor Necrosis Factor / therapeutic use*
Recombinant Fusion Proteins / therapeutic use*
Tumor Necrosis Factor-alpha / antagonists & inhibitors*
Vasculitis / complications*
Vasculitis / drug therapy

Substances

Immunoglobulin Heavy Chains
Immunoglobulin gamma-Chains
Receptors, Tumor Necrosis Factor
Recombinant Fusion Proteins
Tumor Necrosis Factor-alpha
Ro 45-2081